Vitalzym (World Nutrition)

Vitalzym Cardio (formerly VitalzymSEB) was introduced in 2005, after much success of the original Vitalzym, which has become one of the leading systemic enzyme formulations available. Vitalzym Cardio is formulated with your cardiovascular wellbeing in mind. The SEBkinase blend contains "heart healthy" enzymes that may cleanse the blood of excess fibrin and reduce vascular inflammation.*Countless sufferers of chronic conditions such as arthritis, fibromyalgia, systemic inflammation, fibroids, and many more have found relief with the regular use of Vitalzym. A common benefit of Vitalzym has been its ability its ability to cleanse the blood. World Nutrition and Specialty Enzymes have taken the cardiovascular support of Vitalzym and harnessed it with nattokinase and other "heart healthy" nutrients to create an enzyme formulation specifically to support cardiovascular wellness. Vitalzym Cardio also contains powerful antioxidants, such as CoQ10, which has been shown to have significant impact on heart function.*Reduce Fibrin in the BloodThe fibrinolytic enzymes in Vitalzym Cardio have been shown to have the ability to digest excess fibrin (protein buildup) in the blood, which allows for improved blood viscosity. Stacked red blood cells (or Rouleau effect) often reflect poor protein digestion. Symptoms can include fatigue, stress on the heart, and poor circulation. The ingredients in Vitalzym Cardio have been shown, using darkfield microscopy, to significantly reduce the stacking of red blood cells.*C-Reactive ProteinsIncreased vascular inflammation has been recently shown to be a factor in many debilitating issues. C-Reactive Protein levels are used as a marker for vascular inflammation. Then enzymes in Vitalzym Cardio have been shown to reduce the levels of C-Reactive Proteins.*Vitalzym Cardio IngredientsNattokinaseNattokinase is a fibrinolytic enzyme extracted and purified from natto, a fermented soybean food used by the Japanese for thousands of years as a traditional food medicine.Nattokinase was first identified in 1980 by Dr. Hiroyuki Sumi, M.D., Ph.D., who was researching thrombolytic enzymes with the hope of finding a natural agent that could successfully dissolve thrombus associated with cardiac and cerebral infarction (blood clots associated with heart attacks and stroke). After testing more than 200 natural foods as potential thrombolytic agents, Sumi found that natto possessed a substance with a "a potency matched by no other enzyme." Dr. Sumi named the newly discovered enzyme nattikinase.*By dissolving fibrin more completely than any other substance tested by Dr. Sumi, nattokinase may be particularly effective in helping the body fight blood clots. Its thrombolytic activity is enhanced by the enzyme's ability to boost the body's production of both plasmin and other clot-dissolving agents, including endogenous urokinase.*SerrapeptaseSerrapeptase is a proteolytic enzyme that is able to digest dead tissue, blood clots, and cysts. Clinical studies show that serrapeptase induced fibrinolytic, anti-inflammatory, and anti-edemic activity in a number of tissues, and that its anti-inflammatory effects are superior to to other proteolytic enzymes.*Serrapeptase has been used in Europe to treat arterial blockages due to its ability to alleviate arterial inflammation and dissolve blood lots. It has been used to treat arthritis, fibrocystic breast disease, carpal tunnel syndrome, and other fibrinolytic, viral, and inflammatory conditions.*DetoxificationSystemic enzymes will help rid the liver of toxins. Some users will experience a detox reaction to the enzymes, including short-term fatigue, nausea, or headache. Liver detoxification reactions are a beneficial cleansing for the body. Increased water intake can assist in the process; reducing the enzyme dosage will slow the rate of detox. Enzymes also help cleanse metabolic debris and help mainain vital blood quality.* Other Ingredients Maltodextrin, Vegetable Cellulose (Capsule) Suggested Use As a dietary supplement, take 1 capsule three times daily, or more as directed by your healthcare provider. Take capsules at least 30 minutes before a meal, 60 minutes after a meal, or any time in-between meals with water. Warnings If you are pregnant, lactating, taking anti-coagulants, blood thinners, or have a history of thinning blood in your family, do not take this product without direction and supervision from your medical provider. Discontinue use 2 weeks prior to surgery. Keep out of reach of children. Store in a cool, dry place with lid tightly closed. Allergen Info Contains no animal derivatives, artificial flavors, yeast, or gluten. Lactose free and contains no harmful talc. Produced with an enterically coated enzyme.

Serving Size: 3 capsulesCapsules Per Box: 180 Active Ingredients:Proprietary Enzyme Blend 324 mg contains: Bromelain Papain Rutin Amylase Protease Lipase Serrapeptase Amla Extract Other Ingredients: Medium-chain Triglycerides, Starch, Glycerin, Polysaccaride, pH Resistent Enteric Coating, Bees Wax, Glycerin Fatty Acid Ester, Riboflavin, Soy Lecithin and Citric Acid Recommended Dosage:As a dietary supplement, take 3 capsules daily with water. This dosage recommendation is for most users and your healthcare professional may recommend a higher activation amount. Warning: If you are currently taking prescription drugs, consult your healthcare professional prior to use. Serrapeptase, a key ingredient in Vxe, was originally discovered in Japan and is commercially produced there for health applications. It has been used as a substitute for animal-derived enzymes (such as chymotrypsin) because of its stronger effect of decomposing bradykinin. Bradykinin is a protein found in the body that causes an inflammatory response.Serrapeptase must be enteric coated to bypass the stomach acids. Without a protective coating the enzyme will be destroyed by the stomach acids.Bromelain is a plant-derived proteolytic enzyme most noted for its ability to break down proteins. Bromelain has been used therapeutically for over 50 years for its anti-inflammatory properties.Papain is also a plant-derived enzyme used both systemically and in the digestive process to break down proteins.Amylase is an enzyme that breaks down carbohydrates.Lipase is an enzyme that breaks down lipids.Rutin is a flavonoid that is used chiefly for strengthening capullary Blood vessels.Amla, also known as the Indian gooseberry, is a rich source of Vitamin C.Vxe also contains natural additives as part of the blending, stabilization, and enteric coating process. Vxe is all-natural and vegetarian. It does not contain talc or titanium dioxide.100% Non-GMO ingredients. Vitalzym XE is recommended by healthcare professionals worldwide. The unique blend of vegetarian enzymes, flavonoids, and antioxidants has been formulated for 100% absorption in the small intestine. All-Natural Enteric CoatingThe effectiveness of any systemic enzyme is determined by the amount of activity level in the bloodstream after the enzyme has been absorbed from the small intestine. Enzymes that are susceptible to destruction in acidic conditions must be protected for delivery to the small intestine. Systemic enzymes will begin to lose their activity once introduced into the low pH (1.0-3.0) acids of the stomach. The amount of activity loss is dependent upon the individual enzyme and the amount of time it spends in the stomach. Studies have shown that unprotected enzymes can lose up to 100% of their activity in fewer than 30 minutes in pH levels below 3.0. The only reliable method of ensuring that 100% of the enzymes are not destroyed by the stomach acids is to enteric-coat the enzymes. Vxe has been formulated to use an enteric coated gel capsule manufactured under pharmaceutical-grade guidelines.* Vxe, serrapeptase, enzymesThough revolutionary to nutritional enzyme blends, this enteric coating process is similar to that used in todays most advanced products. The capsule has an all-natural shell barrier that allows it to withstand the extremely low pH levels found in the stomach. Once introduced to the pancreatic juices in the duodenum (upper small intestine), the shell barrier breaks down to release the enzymes it contains. The enzymes are then absorbed into the bloodstream through the lining of the small intestine.* The enteric coated gel capsule has been designed to pass both the USP (United States Pharmacopeia) and JP (Japan Pharmacopeia) disintegration tests for enteric coated capsules. Every batch is tested to ensure it meets the agency guidelines before exportation to the U.S.* Please see this great Enzyme Digestion Comparison chart/slides to better understand the enteric coating on this product: http://www.worldnutrition.info/enzyme-choices. Image: Effect of pH on Enzyme Stability. More Concentrated. More Activity. More Stability Powder enzyme blends are available today that use an enteric coating, but they are typically in tablet form (see fig. 1). The disadvantage of these blends is the amount of heat created with compressing the ingredients into a tablet. Enzymes are susceptible to high temperatures and may begin to degrade during the manufacturing process.Vxe is produced under strictly controlled temperature ranges and because of this our LiquidFilled Gel Capsules allow for an enteric coated enzyme to be developed without activity loss from heat.* There are also enzyme formulations available in vegetable and gelatin capsules that claim to have an enteric coating (see fig. 2). An independent laboratory has put these to the test and has yet to find one that passes the US Pharmacopeia standard for enteric coating.In fact, the best performing vegetable capsule tested lost more than 85% of its enzyme activity after being subjected to stomach conditions. In other words, less than 15% of its concentration was available for absorption to the bloodstream. Click here to see the results.Liquid enzyme blends also provide a more uniform dose consistency, because the mixing of liquids allows for optimal particle distribution. In powder formulations, each particle of a different enzyme is different in size, causing greater friction between particles during mixing. Excipients are introduced to powder formulations to increase the mixability, but liquids still provide far more even distribution of ingredients, allowing for more consistent dosages in each capsule.*Enzymes always retain some amount of moisture when they are produced. Enzymes, as proteins, are more susceptible to denaturation at higher moisture. Enzyme powders typically have lower (5-10%) moisture. However, even with lower moisture, enzyme powders will lose some of their activity over time, resulting in a loss of up to 20% of activity over a 12-month period. Vxe contains enzymes with a higher degree of purity and less moisture that, when combined with Medium-Chain Triglycerides (MCT), then decompressed during the manufacturing process, removes the moisture completely. As a result, loss of enzyme activity over time due to moisture will not occur after Vxe is produced. Vxe is manufactured to have a 5-year shelf life with no loss of activity when properly stored in a cool, dry place.* Best ValueThere are many cheap enzyme products available today. However, when comparing the value of each blend, Vxe continues to prove to be the least expensive option due to its unmatched efficacy. High concentrations of active, stable enzymes delivered to the bloodstream allows for the least amount of waste in an oral systemic enzyme supplement. When comparing the amount of pure enzymes delivered to the bloodstream for systemic effect, Vxe offers the best value of any systemic enzyme supplement available today. References: Carroll A., R.: Clinical examination of an enzymatic anti-inflammatory agent in emergency surgery. Arztl. Praxis 24 (1972), 2307. Mazzone A, et al.: Evaluation of Serratia peptidase in acute or chronic inflammation of otorhinolaryngology pathology: a multicentre, double blind, randomized trial versus placebo. J Int Med Res. 1990; 18(5):379-88. Kee W., H. Tan S, L., Lee V. Salmon Y. M.: The treatment of breast engorgement with Serrapeptase: a randomized double blind controlled trial. Singapore Med J. 1989:30(l):48-54. Celebrex article Wall Street Journal 19 April 1999. No author listed: Regular Use of Pain Relievers Can Have Dangerous Results. Kaleidoscope Interactive News, American Medical Association media briefing. July 24, 1997. Enzymes A Drug of the Future, Prof. Heinrich Wrba MD and Otto Pecher MD. Published 1993 Eco Med. Kakinumu A. et al.: Regression of fibrinolysis in scalded rats by administration of serrapeptase. Biochem. Pharmacol. 31:2861-2866,1982. Ernst E., Matrai A.: Oral Therapy with proteolytic enzymes for modifying blood rheology. Klin Wschr. 65 (1987), 994. Kunze R., Ransberger K., et at: Humoral immunomodulatory capacity of proteases in immune complex decomposition and formation. First International symposium on combination therapies, Washington, DC, 1991. Jager H.: Hydrolytic Enzymes in the therapy of HIV disease. Zeitschr. Allgemeinmed., 19 (1990), 160. Bartsch W.: The treatment of herpes zoster using proteolytic enzymes. Der Informierte Arzt. 2 (1974), 424-429.

Original Vitalzym is a hybrid formula that combines systemic and digestive delivery to provide total system support. It contains protease, serrapeptase, papain, bromelain, amylase, lipase, rutin and amla. Vitalzym systemic proteolytic enzyme therapy assists the body in fighting: Autoimmune conditions Fibromyalgia symptoms Uterine Fibroid Tumors Pain and Inflammation Fibrosis of the organs Scar tissue Toxins and impurities in the blood Viruses Our bodies have a variety of functional units, such as a digestive system, an immune system, a cardiovascular system, and a circulatory system, just to name a few. Each system requires energy in order to perform optimally. It just so happens that enzymes provide this much needed energy for the successful completion of each biological function. The Purpose of Enzymes Enzymes are said to be the “sparks of life.” They are considered keys that can unlock the door to a healthier you because they not only help improve digestion and nutrient absorption; they are also responsible for millions of bodily functions. What exactly are enzymes? They are proteins that are responsible for every chemical reaction that goes on in your body; governing all functions related to your tissues, muscles, bones, organs, and cells. Every second of our lives, over 3,000 different enzymes are constantly renewing and changing, often at unbelievable speeds. The Purpose of Enzymes Enzymes are said to be the “sparks of life.” They are considered keys that can unlock the door to a healthier you because they not only help improve digestion and nutrient absorption; they are also responsible for millions of bodily functions. What exactly are enzymes? They are proteins that are responsible for every chemical reaction that goes on in your body; governing all functions related to your tissues, muscles, bones, organs, and cells. Every second of our lives, over 3,000 different enzymes are constantly renewing and changing, often at unbelievable speeds. Enzymes are responsible for everyday bodily processes, such as: Metabolism Digestion Breathing Movement Liver function Immune regulation Viscosity of blood Cellular detoxification Energy production Stamina Ability to utilize vitamins and minerals Enzymes have been studied since the early 1900s. Even though there is over a century's worth of information regarding their use, we still have much to learn about them. Although, one thing is for certain; life as we know it, would not exist without them. Over the last decade, science has uncovered numerous roles for enzymes than ever thought possible, as they literally initiate millions of reactions within your body. In fact, many health care professionals are now advocating the use of enzymes for various conditions and post-operative healing. When referring to enzymatic supplements, it's important to distinguish between those used for digestionand those used systemically. Digestive enzymes are taken orally with food in order to help break down fats, carbohydrates, and proteins for improved digestive function and nutrient absorption. Original Vitalzym can assist with digestion, but are not primarily a digestive enzyme. Systemic enzymes, such as those in original Vitalzym, are taken orally in between meals on an empty stomach. This way they can be absorbed by the intestines into the bloodstream where the body can utilize them for countless bodily processes. Vitalzym Systemic Enzyme Therapy As we age, our body's natural production of enzymes begins to slow down. Some health care professionals believe that our natural production of enzymes starts to decrease after the age of 27. It is not too long after this that many of us begin to notice symptoms of low enzyme production, which can include: Slow wound healing Increased scarring Poor digestion Fibrosis conditions Internal inflammation Dr. Anthony Cichoke, enzyme authority, states in his book, Enzymes and Enzyme Therapy, that "Our body's ability to function, to repair when injured, and to ward off disease is directly related to the strength and numbers of our enzymes.” 1 Supplemental enzymes like those in Original Vitalzym, New Vitalzym andVitalzym Cardio along with proper diet and exercise can help to maintain your normal enzyme levels and balance your body's own repair mechanisms. They can also help reduce the incidence of inflammatory and fibrosis conditions. References 1. Cichoke Enzymes and Enzyme Therapy, (Keats Publishing, Chicago, IL, 2000) 2. Ernst E., Matrai A.: Oral Therapy with proteolytic enzymes for modifying blood rheology. Klin Wschr. 65 (1987), 994. 3. Kunze R., Ransberger K., et at: Humoral immunomodulatory capacity of proteases in immune complex decomposition and formation. First International symposium on combination therapies, Washington, DC, 1991.

Vitalzym Extra Strength Systemic Enzymes Vitalzym Extra Strength soft gels are the world’s leading all-natural, vegetarian systemic enzyme supplement. Vitalzym features an unmatched proprietary blend that includes Serrapeptase, Bromelain, Papain, Rutin, Amylase, Protease, Lipase and Amla Extract. These softgel capsules are available in 60, 180 and 360 count bottles. Vitalzym is the only systemic enzyme on the market today boasting the revolutionary enteric-coated, liquid-gel delivery system. Unlike many of the competitors’ tablet- or powder-based products, Vitalzym’s enteric-coated, liquid-gel system ensures that 100 percent of the enzymes survive the harsh acidic environment of the stomach and reach the small intestine, where they become available for absorption into the bloodstream and then are dispersed throughout the entire body.† What does this mean for you? Bottom line, you’ll be enjoying a smaller, easy-to-swallow capsule, taking less capsules per each dose and less doses per day to receive maximum systemic support. Thanks to Vitalzyms advanced delivery system, superior potency, unrivaled absorption rates and reliable consistency, you won’t need to wait three months to see results. You should feel a difference within weeks, or even days! Features of Vitalzym Extra Strength Vitalzym Extra Strength has been formulated with a technologically advanced delivery system that allows forreduced dosage and vastly increased effectiveness as compared to Original Vitalzym Twice as strong as Original Vitalzym Less cost per dose Enteric coated for ideal release of active ingredients Liquid filled for optimal absorption Half the dose of original Vitalzym Smaller and more convenient packaging, with flip-top lid 100% non-GMO Vegetarian Completely recyclable packagin Systemic Enzymes Help You Feel Better, Look Better, and Live Longer Enzymes are said to be the “sparks of life.” They are considered keys that can unlock the door to a healthier you because they not only help improve digestion and nutrient absorption; they are also responsible for millions of bodily functions. Vitalzym contains potent proteolytic enzymes designed to support health. It is an extremely effective systemic enzyme blend with a high Serrapeptase content. Vitalzym works synergistically to provide total system support. According to Dr. Peter Streichhan, a world-renowned enzyme researcher from Germany, "enzyme mixtures have a wider range of therapeutic advantages than do individual enzymes." 1 Vitalzym is specially engineered to help support: Healthy inflammation response Healthy blood sugar levels Healthy immune systems Healthy joint function And so much more Enzyme authority Dr. Anthony Cichoke says, "Every day, researchers throughout the world are discovering new enzymes and new therapeutic uses for them...Researchers are even studying enzyme replacement therapy devising new treatment methods for diseases that they have historically been unable to treat. This includes many diseases that result from inborn errors of metabolism, such as the inability of the body to make a particular enzyme."

Vitalzym Extra Strength Systemic Enzymes Vitalzym Extra Strength soft gels are the world’s leading all-natural, vegetarian systemic enzyme supplement. Vitalzym features an unmatched proprietary blend that includes Serrapeptase, Bromelain, Papain, Rutin, Amylase, Protease, Lipase and Amla Extract. These softgel capsules are available in 60, 180 and 360 count bottles. Vitalzym is the only systemic enzyme on the market today boasting the revolutionary enteric-coated, liquid-gel delivery system. Unlike many of the competitors’ tablet- or powder-based products, Vitalzym’s enteric-coated, liquid-gel system ensures that 100 percent of the enzymes survive the harsh acidic environment of the stomach and reach the small intestine, where they become available for absorption into the bloodstream and then are dispersed throughout the entire body.† What does this mean for you? Bottom line, you’ll be enjoying a smaller, easy-to-swallow capsule, taking less capsules per each dose and less doses per day to receive maximum systemic support. Thanks to Vitalzyms advanced delivery system, superior potency, unrivaled absorption rates and reliable consistency, you won’t need to wait three months to see results. You should feel a difference within weeks, or even days! Features of Vitalzym Extra Strength Vitalzym Extra Strength has been formulated with a technologically advanced delivery system that allows forreduced dosage and vastly increased effectiveness as compared to Original Vitalzym Twice as strong as Original Vitalzym Less cost per dose Enteric coated for ideal release of active ingredients Liquid filled for optimal absorption Half the dose of original Vitalzym Smaller and more convenient packaging, with flip-top lid 100% non-GMO Vegetarian Completely recyclable packagin Systemic Enzymes Help You Feel Better, Look Better, and Live Longer Enzymes are said to be the “sparks of life.” They are considered keys that can unlock the door to a healthier you because they not only help improve digestion and nutrient absorption; they are also responsible for millions of bodily functions. Vitalzym contains potent proteolytic enzymes designed to support health. It is an extremely effective systemic enzyme blend with a high Serrapeptase content. Vitalzym works synergistically to provide total system support. According to Dr. Peter Streichhan, a world-renowned enzyme researcher from Germany, "enzyme mixtures have a wider range of therapeutic advantages than do individual enzymes." 1 Vitalzym is specially engineered to help support: Healthy inflammation response Healthy blood sugar levels Healthy immune systems Healthy joint function And so much more Enzyme authority Dr. Anthony Cichoke says, "Every day, researchers throughout the world are discovering new enzymes and new therapeutic uses for them...Researchers are even studying enzyme replacement therapy devising new treatment methods for diseases that they have historically been unable to treat. This includes many diseases that result from inborn errors of metabolism, such as the inability of the body to make a particular enzyme."